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Spatial patterns of CTCF sites define the anatomy of TADs and their boundaries

BACKGROUND: Topologically associating domains (TADs) are genomic regions of self-interaction. Additionally, it is known that TAD boundaries are enriched in CTCF binding sites. In turn, CTCF sites are known to be asymmetric, whereby the convergent configuration of a pair of CTCF sites leads to the fo...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Nanni, Luca, Ceri, Stefano, Logie, Colin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422557/
https://ncbi.nlm.nih.gov/pubmed/32782014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02108-x
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