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Immunomodulatory drugs suppress Th1-inducing ability of dendritic cells but enhance Th2-mediated allergic responses

Immunomodulatory drugs (IMiDs), lenalidomide and pomalidomide, are widely used treatments for multiple myeloma; however, they occasionally lead to episodes of itchy skin and rashes. Here, we analyzed the effects of IMiDs on human myeloid dendritic cells (mDCs) as major regulators of Th1 or Th2 respo...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Phan, Vien, Ito, Tomoki, Inaba, Muneo, Azuma, Yoshiko, Kibata, Kayoko, Inagaki-Katashiba, Noriko, Tanaka, Akihiro, Satake, Atsushi, Nomura, Shosaku
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422102/
https://ncbi.nlm.nih.gov/pubmed/32761232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001410
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