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Immunomodulatory drugs suppress Th1-inducing ability of dendritic cells but enhance Th2-mediated allergic responses

Immunomodulatory drugs (IMiDs), lenalidomide and pomalidomide, are widely used treatments for multiple myeloma; however, they occasionally lead to episodes of itchy skin and rashes. Here, we analyzed the effects of IMiDs on human myeloid dendritic cells (mDCs) as major regulators of Th1 or Th2 respo...

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Bibliografiske detaljer
Udgivet i:Blood Adv
Main Authors: Phan, Vien, Ito, Tomoki, Inaba, Muneo, Azuma, Yoshiko, Kibata, Kayoko, Inagaki-Katashiba, Noriko, Tanaka, Akihiro, Satake, Atsushi, Nomura, Shosaku
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422102/
https://ncbi.nlm.nih.gov/pubmed/32761232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001410
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