Immunomodulatory drugs suppress Th1-inducing ability of dendritic cells but enhance Th2-mediated allergic responses

Immunomodulatory drugs (IMiDs), lenalidomide and pomalidomide, are widely used treatments for multiple myeloma; however, they occasionally lead to episodes of itchy skin and rashes. Here, we analyzed the effects of IMiDs on human myeloid dendritic cells (mDCs) as major regulators of Th1 or Th2 respo...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood Adv
Egile Nagusiak: Phan, Vien, Ito, Tomoki, Inaba, Muneo, Azuma, Yoshiko, Kibata, Kayoko, Inagaki-Katashiba, Noriko, Tanaka, Akihiro, Satake, Atsushi, Nomura, Shosaku
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2020
Gaiak:
Immunobiology and Immunotherapy
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422102/
https://ncbi.nlm.nih.gov/pubmed/32761232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001410
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