The immunomodulatory-drug, lenalidomide, sustains and enhances interferon-α production by human plasmacytoid dendritic cells

Background: Lenalidomide (LEN), an immunomodulatory drug (IMiD), is currently used for treatment of multiple myeloma (MM). LEN potentiates T cell and natural killer cell functions. However, the cellular and molecular mechanisms underlying the immunomodulatory effects of LEN remain unclear. We focuse...

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Detalhes bibliográficos
Publicado no:J Blood Med
Main Authors: Kibata, Kayoko, Ito, Tomoki, Inaba, Muneo, Tanaka, Akihiro, Iwata, Ryoichi, Inagaki-Katashiba, Noriko, Phan, Vien, Satake, Atsushi, Nomura, Shosaku
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635835/
https://ncbi.nlm.nih.gov/pubmed/31372079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JBM.S206459
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