Short-Chain Fatty Acids Ameliorate Diabetic Nephropathy via GPR43-Mediated Inhibition of Oxidative Stress and NF-κB Signaling

Diabetic nephropathy (DN) is a chronic low-grade inflammatory disease. Oxidative stress and nuclear factor kappa B (NF-κB) signaling play an important role in the pathogenesis of DN. Short-chain fatty acids (SCFAs) produced from carbohydrate fermentation in the gastrointestinal tract exert positive...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Huang, Wei, Man, Yi, Gao, Chenlin, Zhou, Luping, Gu, Junling, Xu, Huiwen, Wan, Qin, Long, Yang, Chai, Li, Xu, Youhua, Xu, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422068/
https://ncbi.nlm.nih.gov/pubmed/32831998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4074832
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