Paradoxical role for wild type p53 in driving therapy resistance in melanoma

Metastatic melanoma is an aggressive disease, despite recent improvements in therapy. Eradicating all melanoma cells even in drug-sensitive tumors is unsuccessful in patients because a subset of cells can transition to a slow-cycling state, rendering them resistant to most targeted therapy. It is st...

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書誌詳細
出版年:Mol Cell
主要な著者: Webster, Marie R, Fane, Mitchell E, Alicea, Gretchen M, Basu, Subhasree, Kossenkov, Andrew V, Marino, Gloria E, Douglass, Stephen M, Kaur, Amanpreet, Ecker, Brett L, Gnanapradeepan, Keerthana, Ndoye, Abibatou, Kugel, Curtis, Valiga, Alexander, Palmer, Jessica, Liu, Qin, Xu, Xiaowei, Morris, Jessicamarie, Yin, Xiangfan, Wu, Hong, Xu, Wei, Zheng, Cathy, Karakousis, Giorgos C, Amaravadi, Ravi K, Mitchell, Tara C, Almeida, Filipe V, Xiao, Min, Rebecca, Vito W, Wang, Ying-Jie, Schuchter, Lynn M, Herlyn, Meenhard, Murphy, Maureen E, Weeraratna, Ashani T
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419227/
https://ncbi.nlm.nih.gov/pubmed/31836388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.11.009
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