Paradoxical role for wild type p53 in driving therapy resistance in melanoma

Metastatic melanoma is an aggressive disease, despite recent improvements in therapy. Eradicating all melanoma cells even in drug-sensitive tumors is unsuccessful in patients because a subset of cells can transition to a slow-cycling state, rendering them resistant to most targeted therapy. It is st...

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Détails bibliographiques
Publié dans:Mol Cell
Auteurs principaux: Webster, Marie R, Fane, Mitchell E, Alicea, Gretchen M, Basu, Subhasree, Kossenkov, Andrew V, Marino, Gloria E, Douglass, Stephen M, Kaur, Amanpreet, Ecker, Brett L, Gnanapradeepan, Keerthana, Ndoye, Abibatou, Kugel, Curtis, Valiga, Alexander, Palmer, Jessica, Liu, Qin, Xu, Xiaowei, Morris, Jessicamarie, Yin, Xiangfan, Wu, Hong, Xu, Wei, Zheng, Cathy, Karakousis, Giorgos C, Amaravadi, Ravi K, Mitchell, Tara C, Almeida, Filipe V, Xiao, Min, Rebecca, Vito W, Wang, Ying-Jie, Schuchter, Lynn M, Herlyn, Meenhard, Murphy, Maureen E, Weeraratna, Ashani T
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419227/
https://ncbi.nlm.nih.gov/pubmed/31836388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.11.009
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