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Targeting of cancer stem cells by differentiation therapy

Chemoresistance is a hallmark of cancer stem cells (CSCs). To develop novel therapeutic strategies that target CSCs, we established osteosarcoma‐initiating (OSi) cells by introducing the c‐Myc gene into bone marrow stromal cells derived from Ink4a/Arf KO mice. These OSi cells include bipotent commit...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Arima, Yoshimi, Nobusue, Hiroyuki, Saya, Hideyuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419023/
https://ncbi.nlm.nih.gov/pubmed/32462706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14504
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