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Mechanism underlying the development of myeloproliferative neoplasms through mutant calreticulin

Deregulation of cytokine signaling is frequently associated with various pathological conditions, including malignancies. In patients with myeloproliferative neoplasms (MPNs), recurrent somatic mutations in the calreticulin (CALR) gene, which encodes a molecular chaperone that resides in the endopla...

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Bibliografiska uppgifter
I publikationen:Cancer Sci
Huvudupphovsmän: Edahiro, Yoko, Araki, Marito, Komatsu, Norio
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419020/
https://ncbi.nlm.nih.gov/pubmed/32462673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14503
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