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Putative coiled-coil domain-dependent autoinhibition and alternative splicing determine SHTN1’s actin-binding activity
The actin cytoskeleton plays a pivotal role in cell development, morphogenesis, and other cellular functions. Precise control of actin dynamics requires actin-binding proteins (ABPs). Here, we characterize multifarious regulation of SHTN1 (shootin1) and show that, unlike known ABPs, SHTN1’s actin bi...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7418779/ https://ncbi.nlm.nih.gov/pubmed/32371045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.04.025 |
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