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Exploiting replicative stress in gynecological cancers as a therapeutic strategy
Elevated levels of replicative stress in gynecological cancers arising from uncontrolled oncogenic activation, loss of key tumor suppressors, and frequent defects in the DNA repair machinery are an intrinsic vulnerability for therapeutic exploitation. The presence of replication stress activates the...
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| Veröffentlicht in: | Int J Gynecol Cancer |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMJ Publishing Group
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7418601/ https://ncbi.nlm.nih.gov/pubmed/32571890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ijgc-2020-001277 |
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