Ageing and genetic background influence anaesthetic effects in a D. melanogaster model of blunt trauma with brain injury(†)()

BACKGROUND: General anaesthetics interact with the pathophysiological mechanisms of traumatic brain injury (TBI). We used a Drosophila melanogaster (fruit fly) model to test the hypothesis that ageing and genetic background modulate the effect of anaesthetics and hyperoxia on TBI-induced mortality i...

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Bibliografiske detaljer
Udgivet i:Br J Anaesth
Main Authors: Schiffman, Hannah J., Olufs, Zachariah P.G., Lasarev, Michael R., Wassarman, David A., Perouansky, Misha
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Neuroscience and Neuroanaesthesia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418562/
https://ncbi.nlm.nih.gov/pubmed/32466842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bja.2020.03.029
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