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Evidence of sequestration of triclabendazole and associated metabolites by extracellular vesicles of Fasciola hepatica

Fascioliasis is a neglected zoonotic disease that infects humans and ruminant species worldwide. In the absence of vaccines, control of fascioliasis is primarily via anthelminthic treatment with triclabendazole (TCBZ). Parasitic flatworms, including Fasciola hepatica, are active secretors of extrace...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Davis, Chelsea N., Winters, Ana, Milic, Ivana, Devitt, Andrew, Cookson, Alan, Brophy, Peter M., Morphew, Russell M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418001/
https://ncbi.nlm.nih.gov/pubmed/32778698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69970-4
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