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Evidence of sequestration of triclabendazole and associated metabolites by extracellular vesicles of Fasciola hepatica

Fascioliasis is a neglected zoonotic disease that infects humans and ruminant species worldwide. In the absence of vaccines, control of fascioliasis is primarily via anthelminthic treatment with triclabendazole (TCBZ). Parasitic flatworms, including Fasciola hepatica, are active secretors of extrace...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Davis, Chelsea N., Winters, Ana, Milic, Ivana, Devitt, Andrew, Cookson, Alan, Brophy, Peter M., Morphew, Russell M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418001/
https://ncbi.nlm.nih.gov/pubmed/32778698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69970-4
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