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Evidence of sequestration of triclabendazole and associated metabolites by extracellular vesicles of Fasciola hepatica

Fascioliasis is a neglected zoonotic disease that infects humans and ruminant species worldwide. In the absence of vaccines, control of fascioliasis is primarily via anthelminthic treatment with triclabendazole (TCBZ). Parasitic flatworms, including Fasciola hepatica, are active secretors of extrace...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Davis, Chelsea N., Winters, Ana, Milic, Ivana, Devitt, Andrew, Cookson, Alan, Brophy, Peter M., Morphew, Russell M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418001/
https://ncbi.nlm.nih.gov/pubmed/32778698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69970-4
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