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PDLIM7 Synergizes With PDLIM2 and p62/Sqstm1 to Inhibit Inflammatory Signaling by Promoting Degradation of the p65 Subunit of NF-κB

Activation of NF-κB transcription factors is critical for innate immune cells to induce inflammation and fight against microbial pathogens. On the other hand, the excessive and prolonged activation of NF-κB causes massive inflammatory damage to the host, suggesting that regulatory mechanisms to prom...

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Vydáno v:Front Immunol
Hlavní autoři: Jodo, Aya, Shibazaki, Azusa, Onuma, Asuka, Kaisho, Tsuneyasu, Tanaka, Takashi
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417631/
https://ncbi.nlm.nih.gov/pubmed/32849529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01559
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