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Insights Into Dynamics of Inhibitor and Ubiquitin-Like Protein Binding in SARS-CoV-2 Papain-Like Protease

Covid-19 is caused by a novel form of coronavirus for which there are currently no vaccines or anti-viral drugs. This virus, termed SARS-CoV-2 (CoV2), contains Papain-like protease (PLpro) involved in viral replication and immune response evasion. Drugs targeting this protease therefore have great p...

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Détails bibliographiques
Publié dans:Front Mol Biosci
Auteurs principaux: Bosken, Yuliana K., Cholko, Timothy, Lou, Yuan-Chao, Wu, Kuen-Phon, Chang, Chia-en A.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417481/
https://ncbi.nlm.nih.gov/pubmed/32850963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.00174
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