Effect of Venlafaxine on Apnea-Hypopnea Index in Patients With Sleep Apnea: A Randomized, Double-Blind Crossover Study

BACKGROUND: One of the key mechanisms underlying OSA is reduced pharyngeal muscle tone during sleep. Data suggest that pharmacologic augmentation of central serotonergic/adrenergic tone increases pharyngeal muscle tone. RESEARCH QUESTION: We hypothesized that venlafaxine, a serotonin-norepinephrine...

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Detalhes bibliográficos
Publicado no:Chest
Main Authors: Schmickl, Christopher N., Li, Yanru, Orr, Jeremy E., Jen, Rachel, Sands, Scott A., Edwards, Bradley A., DeYoung, Pamela, Owens, Robert L., Malhotra, Atul
Formato: Artigo
Idioma:Inglês
Publicado em: American College of Chest Physicians 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417375/
https://ncbi.nlm.nih.gov/pubmed/32278781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chest.2020.02.074
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