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Targeting CDK4/6 in mantle cell lymphoma
Targeting the cell cycle represents a rational approach to mantle cell lymphoma (MCL) therapy, as aberrant expression of cyclin D1 and dysregulation of CDK4 underlie cell cycle progression and proliferation of MCL cells. Although cell cycle cancer therapy was historically ineffective due to a lack o...
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| Publicado no: | Ann Lymphoma |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7416845/ https://ncbi.nlm.nih.gov/pubmed/32783046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/aol.2019.12.01 |
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