The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients

There is an urgent need to identify antivirals against the coronavirus SARS-CoV-2 in the current COVID-19 pandemic and to contain future similar emergencies early on. Specific side-chain cholesterol oxidation products of the oxysterols family have been shown to inhibit a large variety of both envelo...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Marcello, Alessandro, Civra, Andrea, Milan Bonotto, Rafaela, Nascimento Alves, Lais, Rajasekharan, Sreejith, Giacobone, Chiara, Caccia, Claudio, Cavalli, Roberta, Adami, Marco, Brambilla, Paolo, Lembo, David, Poli, Giuseppe, Leoni, Valerio
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7416714/
https://ncbi.nlm.nih.gov/pubmed/32810737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101682
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