25-Hydroxycholesterol and 27-hydroxycholesterol inhibit human rotavirus infection by sequestering viral particles into late endosomes

A novel innate immune strategy, involving specific cholesterol oxidation products as effectors, has begun to reveal connections between cholesterol metabolism and immune response against viral infections. Indeed, 25-hydroxycholesterol (25HC) and 27-hydroxycholesterol (27HC), physiologically produced...

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Foilsithe in:Redox Biol
Main Authors: Civra, Andrea, Francese, Rachele, Gamba, Paola, Testa, Gabriella, Cagno, Valeria, Poli, Giuseppe, Lembo, David
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2018
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138790/
https://ncbi.nlm.nih.gov/pubmed/30212801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.09.003
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