Insulin-Like Growth Factor I Prevents Cellular Aging via Activation of Mitophagy

Mitochondrial dysfunction is a hallmark of cellular aging. Mitophagy is a critical mitochondrial quality control mechanism that removes dysfunctional mitochondria and contributes to cell survival. Insulin-like growth factor 1 (IGF-1) promotes survival of smooth muscle cells (SMCs), but its potential...

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Detalhes bibliográficos
Publicado no:J Aging Res
Main Authors: Hou, Xuwei, Li, Zhaohui, Higashi, Yusuke, Delafontaine, Patrice, Sukhanov, Sergiy
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7416301/
https://ncbi.nlm.nih.gov/pubmed/32802505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4939310
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