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In vitro metabolic profile and drug‐drug interaction assessment of secnidazole, a high‐dose 5‐nitroimidazole antibiotic for the treatment of bacterial vaginosis
A single‐dose oral granule formulation of secnidazole 2 g (SOLOSEC(™)) has been approved in the US as a treatment for bacterial vaginosis. Available data on the likelihood of in vitro drug‐drug and alcohol‐drug interactions are limited. Secnidazole was incubated with cultured human hepatocytes over...
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| 發表在: | Pharmacol Res Perspect |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7416039/ https://ncbi.nlm.nih.gov/pubmed/32776491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.634 |
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