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Dysfunctional telomeres trigger cellular senescence mediated by cyclic GMP-AMP synthase
Defective DNA damage response (DDR) signaling is a common mechanism that initiates and maintains the cellular senescence phenotype. Dysfunctional telomeres activate DDR signaling, genomic instability, and cellular senescence, but the links among these events remains unclear. Here, using an array of...
Spremljeno u:
| Izdano u: | J Biol Chem |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7415994/ https://ncbi.nlm.nih.gov/pubmed/32540968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012962 |
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