RAD51 interconnects between DNA replication, DNA repair and immunity

RAD51, a multifunctional protein, plays a central role in DNA replication and homologous recombination repair, and is known to be involved in cancer development. We identified a novel role for RAD51 in innate immune response signaling. Defects in RAD51 lead to the accumulation of self-DNA in the cyt...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Bhattacharya, Souparno, Srinivasan, Kalayarasan, Abdisalaam, Salim, Su, Fengtao, Raj, Prithvi, Dozmorov, Igor, Mishra, Ritu, Wakeland, Edward K., Ghose, Subroto, Mukherjee, Shibani, Asaithamby, Aroumougame
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416901/
https://ncbi.nlm.nih.gov/pubmed/28334891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx126
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