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USP7 targeting modulates anti-tumor immune response by reprogramming Tumor-associated Macrophages in Lung Cancer

Background: Tumor associated macrophages (TAMs) have strong plasticity and if reprogrammed, can clear tumor cells and regulate the adaptive immune system for cancer immunotherapy. Deubiquitinating enzymes (DUBs), which can remove ubiquitin (Ub) from Ub-modified substrates, have been associated with...

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Publicat a:Theranostics
Autors principals: Dai, Xiaomeng, Lu, Lisen, Deng, Suke, Meng, Jingshu, Wan, Chao, Huang, Jing, Sun, Yajie, Hu, Yan, Wu, Bian, Wu, Gang, Lovell, Jonathan F., Jin, Honglin, Yang, Kunyu
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415808/
https://ncbi.nlm.nih.gov/pubmed/32802195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.47137
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