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USP7 targeting modulates anti-tumor immune response by reprogramming Tumor-associated Macrophages in Lung Cancer

Background: Tumor associated macrophages (TAMs) have strong plasticity and if reprogrammed, can clear tumor cells and regulate the adaptive immune system for cancer immunotherapy. Deubiquitinating enzymes (DUBs), which can remove ubiquitin (Ub) from Ub-modified substrates, have been associated with...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Dai, Xiaomeng, Lu, Lisen, Deng, Suke, Meng, Jingshu, Wan, Chao, Huang, Jing, Sun, Yajie, Hu, Yan, Wu, Bian, Wu, Gang, Lovell, Jonathan F., Jin, Honglin, Yang, Kunyu
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415808/
https://ncbi.nlm.nih.gov/pubmed/32802195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.47137
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