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Local Mitochondrial ATP Production Regulates Endothelial Fatty Acid Uptake and Transport.
Most organs use fatty acids (FAs) as a key nutrient, but little is known of how blood-borne FAs traverse the endothelium to reach underlying tissues. We conducted a small-molecule screen and identified niclosamide as a suppressor of endothelial FA uptake and transport. Structure/activity relationshi...
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| Publicado no: | Cell Metab |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7415739/ https://ncbi.nlm.nih.gov/pubmed/32521232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.05.018 |
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