Molecular Pathways of Colon Inflammation Induced by Cancer Immunotherapy

Checkpoint blockade with antibodies specific for the PD-1 and CTLA-4 inhibitory receptors can induce durable responses in a wide range of human cancers. However, the immunological mechanisms responsible for severe inflammatory side effects remain poorly understood. Here we report a comprehensive sin...

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Publicado no:Cell
Main Authors: Luoma, Adrienne M., Suo, Shengbao, Williams, Hannah L., Sharova, Tatyana, Sullivan, Keri, Manos, Michael, Bowling, Peter, Hodi, F. Stephen, Rahma, Osama, Sullivan, Ryan J., Boland, Genevieve M., Nowak, Jonathan A., Dougan, Stephanie K., Dougan, Michael, Yuan, Guo-Cheng, Wucherpfennig, Kai W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415717/
https://ncbi.nlm.nih.gov/pubmed/32603654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.06.001
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