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Impaired mesocorticolimbic connectivity underlies increased mechanical pain sensitivity in chronic low back pain

Chronic low back pain (cLBP) is a prevalent disorder. A growing body of evidence linking the pathology of the reward network to chronic pain suggests that pain sensitization may contribute to cLBP chronification via disruptions of mesocortical and mesolimbic circuits in the reward system. Resting-st...

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Detalhes bibliográficos
Publicado no:Neuroimage
Main Authors: Yu, Siyi, Li, Wen, Shen, Wei, Edwards, Robert R., Gollub, Randy L., Wilson, Georgia, Park, Joel, Ortiz, Ana, Cao, Jin, Gerber, Jessica, Mawla, Ishtiaq, Chan, Suk-Tak, Lee, Jeungchan, Wasan, Ajay D., Napadow, Vitaly, Kaptchuk, Ted J., Rosen, Bruce, Kong, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415705/
https://ncbi.nlm.nih.gov/pubmed/32439536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2020.116969
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