Small Cell Carcinoma of the Ovary, Hypercalcaemic Type – genetics, new treatment targets and current management guidelines

Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT) is a rare and highly aggressive ovarian malignancy. In almost all cases, it is associated with somatic and often germline pathogenic variants in SMARCA4, which encodes for the SMARCA4 protein (BRG1), a subunit of the SWI/SNF chromatin re...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Tischkowitz, Marc, Huang, Sidong, Banerjee, Susana, Hague, Jennifer, Hendricks, William P.D., Huntsman, David G., Lang, Jessica D., Orlando, Krystal A., Oza, Amit M., Pautier, Patricia, Ray-Coquard, Isabelle, Trent, Jeffrey M., Witcher, Michael, Witkowski, Leora, McCluggage, W. Glenn, Levine, Douglas A., Foulkes, William D., Weissman, Bernard E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415570/
https://ncbi.nlm.nih.gov/pubmed/32156746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-3797
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