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Signaling via the p75 neurotrophin receptor facilitates amyloid-β-induced dendritic spine pathology
Synapse and dendritic spine loss induced by amyloid-β oligomers is one of the main hallmarks of the early phases of Alzheimer’s disease (AD) and is directly correlated with the cognitive decline typical of this pathology. The p75 neurotrophin receptor (p75(NTR)) binds amyloid-β oligomers in the nM r...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7415136/ https://ncbi.nlm.nih.gov/pubmed/32770070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70153-4 |
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