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Microglia depletion diminishes key elements of the leukotriene pathway in the brain of Alzheimer’s Disease mice

Leukotrienes (LTs) contribute to the neuropathology of chronic neurodegenerative disorders including Alzheimer’s Disease (AD), where they mediate neuroinflammation and neuronal cell-death. In consequence, blocking the action of Leukotrienes (LTs) ameliorates pathologies and improves cognitive functi...

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Dades bibliogràfiques
Publicat a:Acta Neuropathol Commun
Autors principals: Michael, J., Unger, M. S., Poupardin, R., Schernthaner, P., Mrowetz, H., Attems, J., Aigner, L.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414992/
https://ncbi.nlm.nih.gov/pubmed/32771067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00989-4
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