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Microglia depletion diminishes key elements of the leukotriene pathway in the brain of Alzheimer’s Disease mice
Leukotrienes (LTs) contribute to the neuropathology of chronic neurodegenerative disorders including Alzheimer’s Disease (AD), where they mediate neuroinflammation and neuronal cell-death. In consequence, blocking the action of Leukotrienes (LTs) ameliorates pathologies and improves cognitive functi...
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| Publicado no: | Acta Neuropathol Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7414992/ https://ncbi.nlm.nih.gov/pubmed/32771067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00989-4 |
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