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Spray dried VSV-vectored vaccine is thermally stable and immunologically active in vivo

Effective vaccine delivery and coverage to rural and resource-poor countries is hindered by the dependence on cold chain storage. As such, developments of cold chain-free technologies are highly sought. Although spray dried adenoviral vectors have shown long term stability at ambient temperatures an...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Toniolo, Steven P., Afkhami, Sam, D’Agostino, Michael R., Lichty, Brian D., Cranston, Emily D., Xing, Zhou, Thompson, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414861/
https://ncbi.nlm.nih.gov/pubmed/32770018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70325-2
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