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NitroxylFluor: A Thiol-Based Fluorescent Probe for Live-Cell Imaging of Nitroxyl

Detection of nitroxyl (HNO), the transient one-electron reduced form of nitric oxide, is a significant challenge owing to its high reactivity with biological thiols (with rate constants as high as 10(9)M(−1) s(−1)). To address this, we report a new thiol-based HNO-responsive trigger that can compete...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Pino, Nicholas W., Davis, Jerome, Yu, Zhengxin, Chan, Jefferson
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414788/
https://ncbi.nlm.nih.gov/pubmed/29239609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b11471
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