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A selective phosphine-based fluorescent probe for nitroxyl in living cells

A novel fluorescein-based fluorescent probe for nitroxyl (HNO) based on the reductive Staudinger ligation of HNO with an aromatic phosphine was prepared. This probe reacts with HNO derived from Angeli’s salt and 4-bromo Piloty’s acid under physiological conditions without interference by other biolo...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Miao, Zhengrui, Reisz, Julie A., Mitroka, Susan M., Pan, Jia, Xian, Ming, King, S. Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355083/
https://ncbi.nlm.nih.gov/pubmed/25465170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.11.041
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