Demonstrating a reduced capacity for removal of fluid from cerebral white matter and hypoxia in areas of white matter hyperintensity associated with age and dementia

White matter hyperintensities (WMH) occur in association with dementia but the aetiology is unclear. Here we test the hypothesis that there is a combination of impaired elimination of interstitial fluid from the white matter together with a degree of hypoxia in WMH. One of the mechanisms for the eli...

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Veröffentlicht in:Acta Neuropathol Commun
Hauptverfasser: MacGregor Sharp, Matthew, Saito, Satoshi, Keable, Abby, Gatherer, Maureen, Aldea, Roxana, Agarwal, Nivedita, Simpson, Julie E., Wharton, Stephen B., Weller, Roy O., Carare, Roxana O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414710/
https://ncbi.nlm.nih.gov/pubmed/32771063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01009-1
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