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A novel path-specific effect statistic for identifying the differential specific paths in systems epidemiology

BACKGROUND: Biological pathways play an important role in the occurrence, development and recovery of complex diseases, such as cancers, which are multifactorial complex diseases that are generally caused by mutation of multiple genes or dysregulation of pathways. RESULTS: We propose a path-specific...

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Detalhes bibliográficos
Publicado no:BMC Genet
Main Authors: Li, Hongkai, Geng, Zhi, Sun, Xiaoru, Yu, Yuanyuan, Xue, Fuzhong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414699/
https://ncbi.nlm.nih.gov/pubmed/32770935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-020-00876-w
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