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Genotoxic Effects of Etoposide, Bleomycin, and Ethyl Methanesulfonate on Cultured CHO Cells: Analysis by GC-MS/MS and Comet Assay

To evaluate methods for analysis of genotoxic effects on mammalian cell lines, we tested the effect of three common genotoxic agents on Chinese hamster ovary (CHO) cells by single-cell gel electrophoresis (comet assay) and gas chromatography-tandem mass spectrometry (GC-MS/MS). Suspension-grown CHO...

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Bibliografski detalji
Izdano u:J Nucleic Acids
Glavni autori: Atha, Donald H., Coskun, Erdem, Erdem, Onur, Tona, Alessandro, Reipa, Vytas, Nelson, Bryant C.
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414336/
https://ncbi.nlm.nih.gov/pubmed/32802493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8810105
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