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Genotoxic Effects of Etoposide, Bleomycin, and Ethyl Methanesulfonate on Cultured CHO Cells: Analysis by GC-MS/MS and Comet Assay

To evaluate methods for analysis of genotoxic effects on mammalian cell lines, we tested the effect of three common genotoxic agents on Chinese hamster ovary (CHO) cells by single-cell gel electrophoresis (comet assay) and gas chromatography-tandem mass spectrometry (GC-MS/MS). Suspension-grown CHO...

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Bibliografiske detaljer
Udgivet i:J Nucleic Acids
Main Authors: Atha, Donald H., Coskun, Erdem, Erdem, Onur, Tona, Alessandro, Reipa, Vytas, Nelson, Bryant C.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414336/
https://ncbi.nlm.nih.gov/pubmed/32802493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8810105
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