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HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer

Methionine restriction, a dietary regimen that protects against metabolic diseases and aging, represses cancer growth and improves cancer therapy. However, the response of different cancer cells to this nutritional manipulation is highly variable, and the molecular determinants of this heterogeneity...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Xu, Qing, Li, Yuanyuan, Gao, Xia, Kang, Kai, Williams, Jason G., Tong, Lingfeng, Liu, Juan, Ji, Ming, Deterding, Leesa J., Tong, Xuemei, Locasale, Jason W., Li, Leping, Shats, Igor, Li, Xiaoling
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414133/
https://ncbi.nlm.nih.gov/pubmed/32770044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17818-w
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