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Radial shock waves prevent growth retardation caused by the clinically used drug vismodegib in ex vivo cultured bones
In childhood medulloblastoma patients, the hedgehog antagonist vismodegib is an effective anti-cancer treatment but unfortunately induces irreversible growth arrests and growth impairment limiting its use in skeletally immature patients. We hypothesized that radial shock wave treatment (rSWT) may pr...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7414117/ https://ncbi.nlm.nih.gov/pubmed/32770014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69904-0 |
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