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Radial shock waves prevent growth retardation caused by the clinically used drug vismodegib in ex vivo cultured bones

In childhood medulloblastoma patients, the hedgehog antagonist vismodegib is an effective anti-cancer treatment but unfortunately induces irreversible growth arrests and growth impairment limiting its use in skeletally immature patients. We hypothesized that radial shock wave treatment (rSWT) may pr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ramesh, Sowmya, Sävendahl, Lars, Madhuri, Vrisha, Zaman, Farasat
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414117/
https://ncbi.nlm.nih.gov/pubmed/32770014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69904-0
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