M-protein based vaccine induces immunogenicity and protection from Streptococcus pyogenes when delivered on a high-density microarray patch (HD-MAP)

We evaluated vaccination against Streptococcus pyogenes with the candidate vaccine, J8-DT, delivered by a high-density microarray patch (HD-MAP). We showed that vaccination with J8-DT eluted from a coated HD-MAP (J8-DT/HD-MAP), induced similar total IgG responses to that generated by vaccination wit...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:NPJ Vaccines
Prif Awduron: Mills, Jamie-Lee S., Jayashi Flores, Cesar M., Reynolds, Simone, Wun, Christine, Calcutt, Ainslie, Baker, S. Ben, Murugappan, Senthil, Depelsenaire, Alexandra C. I., Dooley, Jessica, Fahey, Paul V., Forster, Angus H., Pandey, Manisha, Good, Michael F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414110/
https://ncbi.nlm.nih.gov/pubmed/32802413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-00222-2
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