M-protein based vaccine induces immunogenicity and protection from Streptococcus pyogenes when delivered on a high-density microarray patch (HD-MAP)

We evaluated vaccination against Streptococcus pyogenes with the candidate vaccine, J8-DT, delivered by a high-density microarray patch (HD-MAP). We showed that vaccination with J8-DT eluted from a coated HD-MAP (J8-DT/HD-MAP), induced similar total IgG responses to that generated by vaccination wit...

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Detalhes bibliográficos
Publicado no:NPJ Vaccines
Main Authors: Mills, Jamie-Lee S., Jayashi Flores, Cesar M., Reynolds, Simone, Wun, Christine, Calcutt, Ainslie, Baker, S. Ben, Murugappan, Senthil, Depelsenaire, Alexandra C. I., Dooley, Jessica, Fahey, Paul V., Forster, Angus H., Pandey, Manisha, Good, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414110/
https://ncbi.nlm.nih.gov/pubmed/32802413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-00222-2
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