Mitochondrial DNA enhance innate immune responses in neuromyelitis optica by monocyte recruitment and activation

Although recent studies indicate the involvement of monocytes in accelerating the lesion formation of neuromyelitis optica spectrum disorder (NMOSD), the precise mechanism of the innate immune system activation remains elusive. Thus, in this study, we aimed to clarify the mechanisms of NMOSD pathoge...

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Udgivet i:Sci Rep
Main Authors: Shimizu, Mikito, Okuno, Tatsusada, Kinoshita, Makoto, Sumi, Hisae, Fujimura, Harutoshi, Yamashita, Kazuya, Sugimoto, Tomoyuki, Sakakibara, Shuhei, Sakakibara, Kaori, Koda, Toru, Tada, Satoru, Ishikura, Teruyuki, Murata, Hisashi, Beppu, Shohei, Shiraishi, Naoyuki, Sugiyama, Yasuko, Nakatsuji, Yuji, Kumanogoh, Atsushi, Mochizuki, Hideki
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414017/
https://ncbi.nlm.nih.gov/pubmed/32764561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70203-x
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