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Platelets docking to VWF prevent leaks during leukocyte extravasation by stimulating Tie-2

Neutrophil extravasation requires opening of the endothelial barrier but does not necessarily cause plasma leakage. Leaks are prevented by contractile actin filaments surrounding the diapedesis pore, keeping this opening tightly closed around the transmigrating neutrophils. We have identified the re...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Braun, Laura J., Stegmeyer, Rebekka I., Schäfer, Kerstin, Volkery, Stefan, Currie, Silke M., Kempe, Birgit, Nottebaum, Astrid F., Vestweber, Dietmar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7413753/
https://ncbi.nlm.nih.gov/pubmed/32369573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003442
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