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Platelets docking to VWF prevent leaks during leukocyte extravasation by stimulating Tie-2

Neutrophil extravasation requires opening of the endothelial barrier but does not necessarily cause plasma leakage. Leaks are prevented by contractile actin filaments surrounding the diapedesis pore, keeping this opening tightly closed around the transmigrating neutrophils. We have identified the re...

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Publicat a:Blood
Autors principals: Braun, Laura J., Stegmeyer, Rebekka I., Schäfer, Kerstin, Volkery, Stefan, Currie, Silke M., Kempe, Birgit, Nottebaum, Astrid F., Vestweber, Dietmar
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7413753/
https://ncbi.nlm.nih.gov/pubmed/32369573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003442
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