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Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING

Recognition of DNA viruses, such as cytomegaloviruses (CMVs), through pattern-recognition receptor (PRR) pathways involving MyD88 or STING constitute a first-line defense against infections mainly through production of type I interferon (IFN-I). However, the role of these pathways in different tissu...

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Enregistré dans:
Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Piersma, Sytse J, Poursine-Laurent, Jennifer, Yang, Liping, Barber, Glen N, Parikh, Bijal A, Yokoyama, Wayne M
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7413665/
https://ncbi.nlm.nih.gov/pubmed/32723479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56882
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