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Instability of aquaglyceroporin (AQP) 2 contributes to drug resistance in Trypanosoma brucei
Defining mode of action is vital for both developing new drugs and predicting potential resistance mechanisms. Sensitivity of African trypanosomes to pentamidine and melarsoprol is predominantly mediated by aquaglyceroporin 2 (TbAQP2), a channel associated with water/glycerol transport. TbAQP2 is ex...
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| Publicado no: | PLoS Negl Trop Dis |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7413563/ https://ncbi.nlm.nih.gov/pubmed/32644992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008458 |
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