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PRMT1-dependent methylation of BRCA1 contributes to the epigenetic defense of breast cancer cells against ionizing radiation

The therapeutic effect of irradiation is thought to come from DNA damage that affects rapidly proliferating cancer cells; however, resistant cells rapidly initiate mechanisms to repair such damage. While DNA repair mechanisms responsible for cancer cell survival following DNA damage are understood,...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Montenegro, María F., González-Guerrero, Rebeca, Sánchez-del-Campo, Luis, Piñero-Madrona, Antonio, Cabezas-Herrera, Juan, Rodríguez-López, José Neptuno
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7413540/
https://ncbi.nlm.nih.gov/pubmed/32764667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70289-3
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