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PRMT1-dependent methylation of BRCA1 contributes to the epigenetic defense of breast cancer cells against ionizing radiation

The therapeutic effect of irradiation is thought to come from DNA damage that affects rapidly proliferating cancer cells; however, resistant cells rapidly initiate mechanisms to repair such damage. While DNA repair mechanisms responsible for cancer cell survival following DNA damage are understood,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Montenegro, María F., González-Guerrero, Rebeca, Sánchez-del-Campo, Luis, Piñero-Madrona, Antonio, Cabezas-Herrera, Juan, Rodríguez-López, José Neptuno
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7413540/
https://ncbi.nlm.nih.gov/pubmed/32764667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70289-3
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