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Deletion of cftr Leads to an Excessive Neutrophilic Response and Defective Tissue Repair in a Zebrafish Model of Sterile Inflammation

Inflammation-related progressive lung destruction is the leading causes of premature death in cystic fibrosis (CF), a genetic disorder caused by a defective cystic fibrosis transmembrane conductance regulator (CFTR). However, therapeutic targeting of inflammation has been hampered by a lack of under...

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Detaylı Bibliyografya
Yayımlandı:Front Immunol
Asıl Yazarlar: Bernut, Audrey, Loynes, Catherine A., Floto, R. Andres, Renshaw, Stephen A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7412881/
https://ncbi.nlm.nih.gov/pubmed/32849617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01733
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